| Rank | Student-Athlete | Time | Meet/Site | Year |
| 1 | Maria Ramirez ** | 21:25.8 | UCR Cross Country Invitational | 2018 |
| 2 | Isabella Glenn* | 21:40.8 | Highlander Invitational | 2021 |
| 3 | Lauren Roberts ** | 21:49.4 | SCIAC Multi-Duals, La Mirada | 2015 |
| 4 | Della Lyle * | 21:51.6 | SCIAC Multi-Duals, La Mirada | 2014 |
| 5 | Avery Kelly | 21:53.0 | Stanford Invite | 2006 |
| 6 | Chloe Bullock* | 22:02.0 | NCAA West Regional, Spokane, Wash. | 2022 |
| 7 | Emily Canales* | 22:03.76 | NCAA Championships, Lake Breeze GC | 2011 |
| 8 | Jessika Snincsak | 22:36.9 | SCIAC Multi-Duals, La Mirada | 2015 |
| 9 | Alexis Wallace | 22:39.7 | Highlander Invitational | 2021 |
| 10 | Etta Eckerstrom | 22:43.1 | SCIAC Multi-Duals, La Mirada | 2015 |
| 11 | Daniella Alvarado | 22:56.6 | SCIAC Multi-Duals, La Mirada | 2015 |
| 12 | Carly Veasy | 22:59.2 | Highlander Invitational | 2019 |
| 13 | Lisa Cohen | 23:07.3 | NCAA Regional, McIver Park | 2003 |
| 14 | Heather Mayer | 23:08.06 | SCIAC Multi-Duals, La Mirada | 2010 |
| 15 | Clara Kerley | 23:13.6 | SCIAC Championships, Prado Park | 2005 |
| 16 | Ellie Ramsey | 23:14.0 | NCAA West Regional Championships | 2018 |
| 17 | Vanessa Anchondo | 23:15.25 | SCIAC Multi-Duals, La Mirada | 2013 |
| 18 | Kaylee Jorgensen | 23:16.2 | SCIAC Multi-Duals, La Mirada | 2016 |
| 19 | Sarah Shipway | 23:16.7 | Highlander Invitational | 2019 |
| 20 | Kelsey DeForge | 23:20.0 | Stanford Invite | 2006 |
Updated through the 2022 season
*Indicates NCAA Championships/national appearance
No 2020 season due to COVID-19